Posts archived in Psychology AS


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Gender differences in immune responses

October 4, 2011 by .

A recent study by Ramona Scotland (just published) is described on a recent edition of Healthcheck (listen here). The study did involve animals but points clearly to significant gender differences – females have stronger immune systems which means they become less ill and recover faster. There is a downside because women are also more susceptible to more autoimmune diseases because their immune systems are more sensitive.

Such differences are important because most research is conducted using men and the assumption is made that the findings apply to all people. For example if a drug is tested on men it may not function in the same way with women.

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Free posters

January 27, 2011 by .

Free posters now available from OUP to brighten your classroom – you can start teaching from this straight away or use it as a revision tool with students.

The pictures are from the new AS Visual Companion.

The sales team who visit your school should have the posters.

Or you can write directly to claire.beatt@oup.com and ask for one.

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Relationships are good for you!

August 1, 2010 by .

Women in our culture generally have richer social networks than men, and this observation has been used as part of the explanation for women coping better with stress and living longer. Now a meta-analysis has shown that a low number of friends, family, colleagues etc. in a person’s social network has similar negative effects on health and longevity as smoking, obesity, sedentary lifestyle or over-use of alcohol. The researchers say that their analysis was not able to differentiate between positive and negative social relationships, so having a good number of positive ones might give an even stronger effect on living healthier and longer!

Holt-Lunstad J, Smith TB, Layton JB. Social Relationships and Mortality Risk: A Meta-analytic Review. PLoS Medicine, 2010; 7 (7):

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Depression and being female

June 19, 2010 by .

We’ve known for ages that far more females than males suffer from depression and anxiety disorders, but it is frequently hypothesised that this is not the true state of things. This is because, in Western industrialised cultures, it is more acceptable to admit vulnerability especially psychological vulnerability if one is female, not male. The macho nature of these cultures is, if you like, a confounding variable. However, there could be more to this than social and cultural relativism.

A recent interesting finding in rats shows that females are definitely more sensitive to stress. Their brain cells respond far more strongly to the precursor to corticosteroid stress hormones, a neurochemical called corticotropin-releasing factor, CRF. Female rat neurons are activated by CRF, male rat neurons adapt to it and less stress hormones are produced.

But does this rat behaviour also happen in humans? Well, we don’t know; but we do know that CRF regulation gets disrupted in human stress-related psychological disorders, so there could be a similarity, although one needs always to be very careful in generalising between species.

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Are you reading this?

June 10, 2010 by .

A student recently pointed out an error in the AS Book on page 119 – in the Do it yourself feature we have suggested that one way to help yourself to remember the terms related to the body’s response to stress is to use more familiar ideas to represent the different words. For example, you might try to remember those Spanish cousins ‘Adrena Cortez’ (the adrenaline junkie) ‘Adrena Medulla’ (with her cortisol habit). However that is the wrong way round – Adrena Cortez has the cortisol habit. Sorry! Thanks to Jasmine Nelson for pointing this out (and telling us how much she liked this blog).

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INFORMATION IS BEAUTIFUL

May 2, 2010 by .

There really are some beautiful charts and diagrams here…. truly ‘descriptive statistics’. I can’t really do any of it justice by cramming it into a tiny blog post, but it’s well worth having a look at this venn diagram about drugs, for example. Or this interactive representation of the link between stress and work.

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New study shows clear link between stress and heart disease

January 20, 2010 by .

A team at the University of London have just published a report of their study linking stress to atheroschlerosis (narrowing of the arteries), which is a major factor in heart attacks. Hamer et al. (2010) worked with 514 healthy men and women (mean age 62.9 years). The participants were given various tasks to increase their stress levels (such as the Stroop task). Cortisol levels in the saliva were measured before and after the stress tasks (cortisol is a hormone produced when we are stressed). Coronary artery calcification (thickening) was also assessed. The study found that only 40% of the participants had raised cortisol levels after the task but of this group there were significantly more people with thickened arteries. These results support the idea that hypothalamic pituitary adrenal activity (which produces cortisol) is a risk factor for CHD.

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Diathesis-Stress and cancer

December 8, 2009 by .

Diathesis-stress is an example of nature AND nurture, as it can be interpreted as a gene or genes switched on by environmental factors. Recently it’s been suggested that being lonely and stressed could affect the expression of cancer-linked genes, triggering their action. The research has been done in the USA on rats, comparing those kept in isolation with those living in groups. The former group had over three times the frequency of breast tumours than the latter group, and their breast tumours were also more aggressive and deadly. The isolated rats also produced more stress hormones and were more reactive to stressful situations. Rats, like ourselves, are social animals and so being isolated is likely to cause stress.

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Stress, Health and Relationships

September 2, 2009 by .

Research due to be published this autumn in the USA journal Cancer suggests that too much stress can impact on surviving cancer. This study was a meta-analysis of 3.8 million people, cancer sufferers diagnosed between 1973 and 2004. Married people were found to have a 5 year survival rate of 63% compared to a 45% rate for those who were separated. The explanation offered is that the stress of a break-up in a serious relationship interferes with healing and recovery, and hence survival rates. The researchers suggest that the love and support of a partner is a key factor in battling illness, even one as serious as cancer, and their findings are supported by many previous studies. Of course, important other factors are also relevant – how many can you think of?

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Stress: Which comes first SAM or HPA?

January 29, 2009 by .

We recently received the question above from Claire Matthews of The Castle School in Bristol and thought some of you would be interested in the answer: The SAM system concerns the adrenal medulla and the release of adrenaline/noradrenaline which has the effect of creating physiological (sympathetic) arousal and producing the fight or flight response. The HPA access concerns the adrenal cortex which produces corticosteroids such as cortisol, which help the body to recover after stress but also have negative effects e.g. reduced immune function. Now to the question – do they happen simultaneously or does the SAM system come first and the HPA second?

The answer is both. Essentially both systems are triggered by a stressor but one (SAM) is an instantaneous response like lighting a match, whereas the other (HPA) is much slower and doesn’t happen very easily (like lighting a fire). It is harder to achieve (needs a continuing stressor) and is only activated in more extreme circumstances. So in a sense the HPA response does come second because, even though it is triggered at the same time as the SAM, its response is seen some time later – well after the fight/flight response.

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